체루비즘: 2예 보고
Cherubism: Review of 2 Cases
곽주희, 김지연, 김명래, 김선종,
소속 상세정보
곽주희 ( Kwak Ju-Hee ) - 이화여자대학교 의학전문대학원 목동병원 구강악안면외과
김지연 ( Kim Ji-Youn ) - 이화여자대학교 의학전문대학원 목동병원 구강악안면외과
김명래 ( Kim Myung-Rae ) - 이화여자대학교 의학전문대학원 목동병원 구강악안면외과
김선종 ( Kim Sun-Jong ) - 이화여자대학교 의학전문대학원 목동병원 구강악안면외과
KMID : 0360120120340050357
Abstract
Cherubism is a rare familial disease of childhood, characterized by proliferative lesion, which is within the maxilla and mandible. In a typical case, painless symmetric expansile lesions develop in the jaws. It shows substitution of the bone by proliferating fibrous tissue exhibiting mature fibroblasts and a number of multinucleated giant cells within an intercellular matrix. Usually, the disease manifests in early childhood, and becomes more marked until puberty, at which time the bony lesions begin to regress. As such, conservative approaches to management are advisable. However, excision of tissue through enucleation or curettage appears to be necessary in more aggressive cases, to reduce the maxillofacial deformity after puberty and to ensure a successful outcome without the risk of progression, requiring additional resection. This report describes 2 cases of manifestation of cherubism of oral and maxillofacial region. We present diagnosis, radiological - histopathologic features, and treatment of cherubism.
키워드
Cherubism;Giant cells;Genes dominant;Maxilla;Mandible
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